The programme includes contributions from a number of Doctor Who stars, including Peter Davison, Katy Manning, Louise Jameson and Janet Fielding.
Doctor Who was largely recorded at the TV Center for its original run between 1963 and 1989. Since it returned in 2005, the show has been produced in Cardiff.
The building was first opened in Shepherd's Bush in 1960. The BBC are selling TVC as part of the corporation's move to Salford.
The 90-minute documentary will be shown on BBC Four at 9.00pm tonight, while a pre-watershed version will air on the channel on Sunday at 7.00pm.